Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454719 | 0.95 | PTGER4 (0.43) | NPSR1HPGDCXCR2GAAALK | |
| SCHEMBL18767461 | 0.93 | NPSR1 (0.46) | NPSR1HPGDCXCR2GAASIRT2 | |
| SCHEMBL21913009 | 0.91 | NPSR1 (0.50) | NPSR1HPGDGAASIRT2SIRT1 | |
| SCHEMBL21913591 | 0.90 | HPGD (0.50) | NPSR1HPGDCXCR2GAANPC1 | |
| SCHEMBL1931336 | 0.86 | NPSR1 (0.53) | NPSR1HPGDGAAALKMAPT | |
| SCHEMBL24174910 | 0.85 | NPSR1 (0.59) | NPSR1HPGDGAAMAPTMEN1 | |
| SCHEMBL17661366 | 0.85 | NPSR1 (0.51) | NPSR1SIRT2SIRT1ALKMAPT | |
| SCHEMBL18767471 | 0.83 | SIRT2 (0.47) | NPSR1HPGDGAASIRT2SIRT1 | |
| SCHEMBL17661457 | 0.83 | ALK (0.47) | NPSR1HPGDGAASIRT2SIRT1 | |
| SCHEMBL17660874 | 0.83 | NPSR1 (0.47) | NPSR1HPGDGAAALKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |