SCHEMBL21914814

SCHEMBL21914814

CC(Oc1ccc(-c2nc(C3CC3)n[nH]2)c(F)c1)/C(=C/F)CN

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 19/20 0.49
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889047 0.81 AOC3 (0.69) AOC3
SCHEMBL21889216 0.70 MAOB (0.43) AOC3
SCHEMBL21889196 0.67 AOC3 (0.69) AOC3
SCHEMBL21914811 0.66 AOC3 (0.46) AOC3
SCHEMBL21914538 0.66 AOC3 (0.59) AOC3
SCHEMBL21889539 0.65 AOC3 (1.00) AOC3
SCHEMBL23590417 0.64 AOC3 (0.67) AOC3
SCHEMBL21889175 0.63 AOC3 (0.67) AOC3
SCHEMBL21889002 0.63 AOC3 (0.67) AOC3
SCHEMBL21914380 0.63 AOC3 (0.68) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed