Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640548 | 0.89 | CYP19A1 (0.47) | CYP19A1HDAC6MAPTL3MBTL1HSD17B1 | |
| SCHEMBL17640580 | 0.87 | CYP19A1 (0.45) | CYP19A1HDAC6MAPTL3MBTL1HSD17B1 | |
| SCHEMBL17640576 | 0.87 | CYP19A1 (0.45) | CYP19A1HDAC6MAPTL3MBTL1HSD17B1 | |
| SCHEMBL17640487 | 0.87 | CYP19A1 (0.50) | CYP19A1MAPTKDM4EATML3MBTL1 | |
| SCHEMBL21915610 | 0.85 | CYP19A1 (0.38) | CYP19A1MAPTKDM4EATML3MBTL1 | |
| SCHEMBL14296800 | 0.83 | KDM4E (0.47) | HDAC6KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL17640612 | 0.81 | CYP19A1 (0.40) | CYP19A1HDAC6MAPTHSD17B1HSD17B2 | |
| SCHEMBL16174618 | 0.81 | KDM4E (0.52) | HDAC6KDM4EATML3MBTL1HDAC4 | |
| SCHEMBL21915416 | 0.81 | HDAC6 (0.41) | CYP19A1HDAC6MAPTKDM4EHSD17B1 | |
| SCHEMBL21915628 | 0.81 | CYP19A1 (0.40) | CYP19A1HDAC6MAPTL3MBTL1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020062375-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉尚赛光电科技有限公司 | 2020-04-02 | — | — | WO | disclosed |