Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146376 | 0.75 | HTT (0.32) | HTTPDGFRBLMNA | |
| SCHEMBL22619366 | 0.71 | PDGFRB (0.38) | HTTPDGFRBLMNA | |
| SCHEMBL22619303 | 0.71 | PDGFRB (0.45) | HTTPDGFRBLMNA | |
| SCHEMBL18659117 | 0.69 | NSD2 (0.39) | HTTPDGFRBLMNA | |
| SCHEMBL18058207 | 0.66 | HTT (0.31) | HTTPDGFRB | |
| SCHEMBL26284158 | 0.59 | GAA (0.41) | HTTPDGFRBLMNA | |
| SCHEMBL17995385 | 0.59 | — | — | |
| SCHEMBL21912879 | 0.57 | PDGFRB (0.41) | HTTPDGFRBLMNA | |
| SCHEMBL30541821 | 0.57 | PDGFRB (0.73) | HTTPDGFRBLMNA | |
| SCHEMBL18273728 | 0.57 | CHRM2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321246-B1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-04-15 | — | — | EP | disclosed |