Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15587256 | 0.88 | MAP4K4 (0.69) | MAP4K4 | |
| SCHEMBL15587989 | 0.87 | MAP4K4 (0.78) | MAP4K4 | |
| SCHEMBL15587774 | 0.83 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL21925379 | 0.83 | MAP4K4 (0.71) | MAP4K4 | |
| SCHEMBL18135276 | 0.82 | MAP4K4 (0.72) | MAP4K4 | |
| Hydrochloric Acid SCHEMBL18984684 | 0.82 | MAP4K4 (0.98) | MAP4K4 | |
| SCHEMBL15587258 | 0.81 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15587252 | 0.81 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL31060266 | 0.81 | MAP4K4 (1.00) | MAP4K4 | |
| SCHEMBL15537852 | 0.81 | MAP4K4 (0.85) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855459-B1 | AMINOQUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-04-29 | — | — | EP | disclosed |