Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21924454 | 0.81 | ELANE (0.42) | ELANEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20945158 | 0.71 | ELANE (0.39) | ELANE | |
| SCHEMBL20945015 | 0.69 | ELANE (0.44) | ELANEPARP1NPC1RAB9ABRD4 | |
| SCHEMBL5116947 | 0.68 | ELANE (0.48) | ELANEPARP1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL20944983 | 0.67 | ELANE (0.50) | ELANEKMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL197253 | 0.67 | ELANE (0.49) | ELANEPARP1MEN1KMT2ARAB9A | |
| SCHEMBL13075504 | 0.67 | ELANE (0.46) | ELANEPARP1MEN1KMT2AHTT | |
| SCHEMBL3724946 | 0.65 | ELANE (0.48) | ELANEPARP1BRD4BRD2BRD3 | |
| SCHEMBL8649103 | 0.65 | ELANE (0.51) | ELANEKMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL13923526 | 0.65 | ELANE (0.46) | ELANEPARP1MEN1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478671-B1 | PYRIDAZINONE-BASED BROAD SPECTRUM ANTI-INFLUENZA INHIBITORS | HOFFMANN LA ROCHE (CH) | 2020-05-13 | — | — | EP | disclosed |