Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.86 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.59 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.57 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.57 |
| ▸ | KIT | P10721 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | STK10 | O94804 | 2/20 | 0.57 |
| ▸ | YES1 | P07947 | 2/20 | 0.57 |
| ▸ | TEC | P42680 | 2/20 | 0.57 |
| ▸ | BTK | Q06187 | 2/20 | 0.57 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.57 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.57 |
| ▸ | CIT | O14578 | 1/20 | 0.57 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.57 |
| ▸ | GAK | O14976 | 1/20 | 0.57 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.57 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15090523 | 0.93 | EGFR (1.00) | EGFRERBB3DUS2KDRERBB2 | |
| SCHEMBL15090691 | 0.86 | EGFR (1.00) | EGFRERBB3DUS2KDRERBB2 | |
| Hydrochloric Acid SCHEMBL15090716 | 0.86 | EGFR (0.99) | EGFRERBB3DUS2KDRERBB2 | |
| SCHEMBL15105017 | 0.86 | EGFR (0.86) | EGFRERBB2ERBB4SRCGAK | |
| SCHEMBL15090516 | 0.86 | EGFR (0.86) | EGFRERBB2ERBB4SRCGAK | |
| SCHEMBL15090527 | 0.85 | EGFR (0.84) | EGFRERBB2ERBB4SRCGAK | |
| SCHEMBL15090569 | 0.85 | EGFR (0.84) | EGFRERBB2ERBB4SRCGAK | |
| SCHEMBL15090537 | 0.84 | EGFR (1.00) | EGFRERBB3DUS2KDRERBB2 | |
| Hydrochloric Acid SCHEMBL15104756 | 0.84 | EGFR (0.83) | EGFRERBB2ERBB4SRCGAK | |
| Hydrochloric Acid SCHEMBL15090765 | 0.84 | EGFR (0.83) | EGFRERBB2ERBB4SRCGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395811-B1 | CRYSTALS OF QUINAZOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR | XUANZHU PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | claimed |