Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19310082 | 0.91 | DDB1 (0.33) | DDB1CRBNIKZF3BDKRB1AKR1B1 | |
| SCHEMBL19310148 | 0.85 | DDB1 (0.33) | DDB1CRBNIKZF3 | |
| SCHEMBL19541643 | 0.84 | CRBN (0.44) | DDB1CRBNIKZF3BDKRB1 | |
| SCHEMBL21924346 | 0.83 | BDKRB1 (0.34) | DDB1CRBNIKZF3BDKRB1AKR1B1 | |
| SCHEMBL21281555 | 0.81 | CRBN (0.52) | DDB1CRBNIKZF3 | |
| SCHEMBL19309923 | 0.81 | CRBN (0.37) | DDB1CRBNIKZF3AKR1B1 | |
| SCHEMBL21927110 | 0.81 | CRBN (0.35) | DDB1CRBNIKZF3BDKRB1 | |
| SCHEMBL23939053 | 0.80 | CRBN (0.38) | DDB1CRBNIKZF3BDKRB1AKR1B1 | |
| SCHEMBL21927093 | 0.80 | CRBN (0.39) | DDB1CRBNIKZF3BDKRB1 | |
| SCHEMBL19541513 | 0.80 | CRBN (0.44) | DDB1CRBNIKZF3BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643709-A1 | ISOINDOLINE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Kangpu Biopharmaceuticals, Ltd. (CN) | 2020-04-29 | — | — | EP | disclosed |