Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369162 | 0.92 | ESR2 (0.46) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL20806237 | 0.90 | ESR2 (0.45) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL21134134 | 0.84 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL18464807 | 0.84 | ESR2 (0.40) | ESR1ESR2 | |
| SCHEMBL18464805 | 0.83 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL19119566 | 0.83 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL25070528 | 0.82 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL18464327 | 0.82 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL20806070 | 0.80 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL21241717 | 0.80 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400270-B1 | DEVICE FOR REGULATING ENTRY OF LIGHT | MERCK PATENT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |