Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935412 | 0.94 | CHRM1 (0.71) | CHRM1 | |
| SCHEMBL31668928 | 0.90 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL21873404 | 0.90 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL31668985 | 0.86 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL21873382 | 0.86 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL30428359 | 0.85 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL21873400 | 0.85 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL21873365 | 0.84 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL18756185 | 0.84 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL30428197 | 0.84 | CHRM1 (0.49) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643718-B1 | HETEROCYCLIC COMPOUND AND ITS USE AS POSITIVE ALLOSTERIC MODULATOR OF THE CHOLINERGIC MUSCARINIC M1 RECEPTOR. | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-26 | — | — | EP | disclosed |
| EP-3643718-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-04-29 | — | — | EP | disclosed |