Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 14/20 | 0.71 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119570 | 1.00 | PTGFR (0.71) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL21546227 | 0.98 | PTGFR (0.74) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119717 | 0.98 | PTGFR (0.74) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL13949002 | 0.97 | PTGFR (0.69) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119609 | 0.95 | PTGFR (0.73) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119720 | 0.95 | PTGFR (0.73) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119709 | 0.94 | PTGFR (0.72) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119611 | 0.92 | PTGFR (0.69) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL13327998 | 0.92 | PTGFR (0.69) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL12119620 | 0.91 | PTGFR (0.68) | PTGFRPTGER3ABCC4ABCB11TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643702-A1 | PROSTAGLANDIN DERIVATIVES | Nicox S.A. (FR) | 2020-04-29 | — | — | EP | disclosed |