Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20606889 | 0.77 | IKBKB (0.34) | MAPTXBP1HTT | |
| SCHEMBL21940280 | 0.77 | S1PR2 (0.33) | S1PR2 | |
| SCHEMBL20606887 | 0.76 | S1PR2 (0.50) | S1PR2HTT | |
| SCHEMBL21940475 | 0.73 | S1PR2 (0.42) | S1PR2HTT | |
| SCHEMBL21940282 | 0.71 | S1PR2 (0.41) | S1PR2HTT | |
| SCHEMBL16301303 | 0.66 | HSP90AB1 (0.40) | MAPTHTT | |
| SCHEMBL26067064 | 0.66 | NOTUM (0.49) | HTT | |
| SCHEMBL2195834 | 0.66 | HTT (0.31) | HTT | |
| SCHEMBL29314750 | 0.65 | HSP90AB1 (0.39) | — | |
| SCHEMBL3454150 | 0.65 | DPYD (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |