Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093793 | 0.83 | SCN9A (0.42) | SCN9ACHUKCNR2CNR1SCN5A | |
| SCHEMBL15968098 | 0.80 | CHUK (0.38) | SCN9ACHUKCNR2CNR1 | |
| SCHEMBL2116352 | 0.80 | CDK2 (0.39) | CNR2CDK2CCNA2CDK1CCNB1 | |
| SCHEMBL15599219 | 0.80 | SSTR4 (0.44) | SCN9ACHUKCNR2CNR1SCN5A | |
| Hydrochloric Acid SCHEMBL15669989 | 0.80 | CNR2 (0.39) | SCN9ACNR2CNR1 | |
| SCHEMBL2112932 | 0.78 | CNR1 (0.54) | CNR2CNR1ALOX5APFEN1 | |
| SCHEMBL18400077 | 0.78 | SCN9A (0.38) | SCN9ACHUKCNR2CNR1CDK2 | |
| SCHEMBL15669947 | 0.78 | CNR1 (0.38) | SCN9ACNR2CNR1CDK2CCNA2 | |
| SCHEMBL15350300 | 0.77 | CNR2 (0.39) | SCN9ACHUKCNR2CNR1SCN5A | |
| SCHEMBL21940549 | 0.76 | CNR2 (0.39) | CNR2CNR1CDK2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |