Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | PDE8A | O60658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175131 | 0.83 | SCN9A (0.44) | SCN9ACYP3A4CYP2C9LMNATSHR | |
| SCHEMBL16858566 | 0.83 | SCN9A (0.44) | SCN9ACYP3A4CYP2C9SCN5A | |
| SCHEMBL4550342 | 0.80 | SCN9A (0.40) | SCN9ACYP3A4CYP2C9SCN5AHTR2A | |
| SCHEMBL17947491 | 0.79 | SCN9A (0.39) | SCN9ACYP3A4CYP2C9LMNATSHR | |
| SCHEMBL15599216 | 0.79 | SCN9A (0.44) | SCN9ACYP3A4CYP2C9LMNATSHR | |
| Hydrochloric Acid SCHEMBL2717080 | 0.79 | SCN9A (0.39) | SCN9ACYP3A4CYP2C9SCN5AHTR2A | |
| SCHEMBL17292928 | 0.79 | HCRTR1 (0.34) | SCN9ACYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4550399 | 0.78 | SCN9A (0.39) | SCN9ACYP3A4CYP2C9SCN5A | |
| SCHEMBL2713741 | 0.77 | SCN9A (0.40) | SCN9ACYP3A4CYP2C9SMN1; SMN2SCN5A | |
| SCHEMBL21940790 | 0.77 | AAK1 (0.34) | SCN9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |