Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 14/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940874 | 1.00 | PTPN11 (0.39) | PTPN11HTR2AKCNH2SLC6A2SLC6A4 | |
| SCHEMBL21940659 | 0.85 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL24388823 | 0.85 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL23046087 | 0.85 | PTPN11 (0.47) | PTPN11KCNH2 | |
| SCHEMBL24091153 | 0.82 | PTPN11 (0.40) | PTPN11HTR2AKCNH2 | |
| SCHEMBL25699157 | 0.82 | PTPN11 (0.37) | PTPN11HTR2AKCNH2 | |
| SCHEMBL25523410 | 0.80 | HTR2A (0.43) | PTPN11HTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL29804135 | 0.78 | HTR2A (0.42) | PTPN11HTR2AKCNH2 | |
| SCHEMBL24672585 | 0.78 | SLC6A4 (0.49) | PTPN11KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21397423 | 0.75 | HTR2A (0.39) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3867238-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2020081848-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-04-23 | — | — | WO | disclosed |