Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methylpiperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL2222437 | 0.98 | PHGDH (0.31) | PHGDH | |
| Piperazine SCHEMBL28127249 | 0.94 | CXCR4 (0.32) | — | |
| SCHEMBL8200666 | 0.94 | CXCR4 (0.32) | — | |
| SCHEMBL8697341 | 0.94 | CXCR4 (0.32) | — | |
| SCHEMBL5979250 | 0.94 | CXCR4 (0.32) | — | |
| SCHEMBL8048064 | 0.94 | CXCR4 (0.32) | — | |
| SCHEMBL3862489 | 0.89 | PHGDH (0.31) | PHGDH | |
| SCHEMBL26927 | 0.89 | — | — | |
| SCHEMBL1189011 | 0.89 | — | — | |
| SCHEMBL2164248 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816078-B2 | Acidic gas removal by aqueous amine solvents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-08-26 | — | — | US | disclosed |
| US-20110171093-A1 | ACIDIC GAS REMOVAL BY AQUEOUS AMINE SOLVENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2011-07-14 | — | — | US | disclosed |