Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.58 |
| ▸ | BCR | P11274 | 7/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.56 |
| ▸ | LDLR | P01130 | 3/20 | 0.56 |
| ▸ | KIT | P10721 | 3/20 | 0.56 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.56 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.56 |
| ▸ | STK10 | O94804 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | FYN | P06241 | 2/20 | 0.56 |
| ▸ | YES1 | P07947 | 2/20 | 0.56 |
| ▸ | LYN | P07948 | 2/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | HCK | P08631 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 2/20 | 0.56 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.56 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.56 |
| ▸ | FECH | P22830 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21943637 | 0.88 | ABL1 (0.54) | ABL1BCRPDGFRBLDLRKIT | |
| SCHEMBL21943413 | 0.87 | LCK (0.67) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21943634 | 0.81 | ABL1 (0.55) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21943425 | 0.79 | MAPK14 (0.56) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21943759 | 0.79 | LDLR (0.62) | ABL1BCRPDGFRBLDLRKIT | |
| SCHEMBL21943424 | 0.77 | BRAF (0.68) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21942991 | 0.77 | BRAF (0.66) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21943000 | 0.76 | LDLR (0.63) | ABL1BCRPDGFRBLDLRKIT | |
| SCHEMBL21943725 | 0.76 | ABL1 (0.78) | ABL1BCRPDGFRBKITEPHB6 | |
| SCHEMBL21944046 | 0.76 | BRAF (0.66) | ABL1BCRPDGFRBKITEPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319322-B2 | Substituted aryl ether compound, preparation method thereof, pharmaceutical composition and use thereof | XIAMEN UNIVERSITY (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20200123162-A1 | SUBSTITUTED ARYL ETHER COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | XIAMEN UNIVERSITY (CN) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123162-A1 | SUBSTITUTED ARYL ETHER COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | CYP4A11, CYP2D6, CYP3A43 | ABL1 78/4885BCR 414/4885PDGFRB 1488/4885 |
| US-11319322-B2 | Substituted aryl ether compound, preparation method thereof, pharmaceutical composition and use thereof | CYP4A11, CYP2D6, CYP3A43 | ABL1 78/4885BCR 414/4885PDGFRB 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.