Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686920 | 1.00 | BCHE (0.53) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL18716356 | 0.82 | BCHE (0.50) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL20556249 | 0.80 | BCHE (0.52) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL4182846 | 0.78 | BCHE (0.59) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL21338588 | 0.71 | BCHE (0.52) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL17137316 | 0.71 | BCHE (0.52) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL23995897 | 0.71 | BCHE (0.62) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL17925924 | 0.71 | BCHE (0.62) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL7087370 | 0.71 | BCHE (0.51) | BCHEACHEPSEN1PSEN2APH1B | |
| SCHEMBL4031189 | 0.71 | BCHE (0.51) | BCHEACHEPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |