Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342896 | 0.89 | KDM4E (0.50) | TYK2 | |
| SCHEMBL20689018 | 0.82 | KDM4E (0.52) | TYK2 | |
| SCHEMBL22342884 | 0.80 | TYK2 (0.66) | TYK2 | |
| SCHEMBL17980683 | 0.77 | GSK3B (0.47) | TYK2 | |
| SCHEMBL21726359 | 0.76 | TYK2 (1.00) | TYK2 | |
| SCHEMBL20679020 | 0.76 | TYK2 (0.83) | TYK2 | |
| SCHEMBL21246344 | 0.76 | TYK2 (0.69) | TYK2 | |
| SCHEMBL22324084 | 0.76 | TYK2 (0.61) | TYK2 | |
| SCHEMBL23772369 | 0.76 | CDK2 (0.46) | TYK2 | |
| SCHEMBL20689133 | 0.75 | CDK2 (0.45) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162944-A1 | SUBSTITUTED 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2021-08-19 | — | — | WO | disclosed |
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |