Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24927397 | 0.84 | S1PR1 (0.39) | GAAMEN1KMT2A | |
| SCHEMBL23594060 | 0.81 | GAA (0.36) | ALDH1A1GAATSHRALOX15HSD17B10 | |
| SCHEMBL23594066 | 0.79 | GAA (0.34) | ALDH1A1GAATSHRALOX15HSD17B10 | |
| SCHEMBL17173050 | 0.78 | GAA (0.44) | ALDH1A1GAATSHRALOX15HSD17B10 | |
| SCHEMBL8315958 | 0.77 | KDM4E (0.34) | GAATSHRKDM4E | |
| SCHEMBL7904692 | 0.76 | GAA (0.63) | ALDH1A1GAAHSD11B1TSHRALOX15 | |
| SCHEMBL3767691 | 0.76 | GAA (0.48) | ALDH1A1GAAHSD11B1TSHRALOX15 | |
| SCHEMBL13403911 | 0.75 | CPN1 (0.41) | ALDH1A1NPSR1 | |
| SCHEMBL14452839 | 0.74 | GAA (0.73) | ALDH1A1GAAHSD11B1TSHRALOX15 | |
| SCHEMBL12359194 | 0.73 | GAA (0.77) | ALDH1A1GAAHSD11B1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081450-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2020-04-23 | — | — | WO | disclosed |