Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687970 | 1.00 | TYK2 (0.83) | TYK2 | |
| SCHEMBL21961744 | 0.99 | TYK2 (0.83) | TYK2 | |
| SCHEMBL21948242 | 0.98 | TYK2 (0.85) | TYK2 | |
| SCHEMBL20688749 | 0.97 | TYK2 (0.86) | TYK2 | |
| SCHEMBL21947136 | 0.97 | TYK2 (0.88) | TYK2 | |
| SCHEMBL21948104 | 0.93 | TYK2 (0.91) | TYK2 | |
| SCHEMBL20688419 | 0.92 | TYK2 (0.84) | TYK2 | |
| SCHEMBL21285365 | 0.91 | TYK2 (0.87) | TYK2 | |
| SCHEMBL21726365 | 0.91 | TYK2 (0.87) | TYK2 | |
| SCHEMBL20688593 | 0.91 | TYK2 (0.82) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |