Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21961732 | 0.94 | TYK2 (0.53) | TYK2 | |
| SCHEMBL21948943 | 0.92 | TYK2 (0.50) | TYK2 | |
| SCHEMBL21948941 | 0.92 | TYK2 (0.50) | TYK2 | |
| SCHEMBL21948944 | 0.92 | TYK2 (0.50) | TYK2 | |
| SCHEMBL21961714 | 0.91 | TYK2 (0.59) | TYK2 | |
| SCHEMBL21947265 | 0.91 | TYK2 (0.55) | TYK2 | |
| SCHEMBL20688000 | 0.91 | TYK2 (0.58) | TYK2 | |
| SCHEMBL20689096 | 0.91 | TYK2 (0.58) | TYK2 | |
| SCHEMBL20688989 | 0.90 | TYK2 (0.54) | TYK2 | |
| SCHEMBL21948934 | 0.87 | TYK2 (0.55) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |