Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21948527 | 0.97 | TYK2 (0.73) | TYK2 | |
| SCHEMBL21948926 | 0.95 | TYK2 (0.79) | TYK2 | |
| SCHEMBL21948914 | 0.90 | TYK2 (0.81) | TYK2 | |
| SCHEMBL21961495 | 0.89 | TYK2 (0.82) | TYK2 | |
| SCHEMBL21962037 | 0.88 | TYK2 (0.92) | TYK2 | |
| SCHEMBL21948860 | 0.88 | TYK2 (0.92) | TYK2 | |
| SCHEMBL21947157 | 0.88 | TYK2 (0.92) | TYK2 | |
| SCHEMBL21854829 | 0.88 | TYK2 (0.92) | TYK2 | |
| SCHEMBL21948855 | 0.88 | TYK2 (0.92) | TYK2 | |
| SCHEMBL21947285 | 0.86 | TYK2 (0.61) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |