SCHEMBL2194902

SCHEMBL2194902

NCCC(=O)OC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
FABP5 Q01469 3/20 0.46
FABP7 O15540 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
EPHX2 P34913 1/20 0.44
HTR2A P28223 1/20 0.43
CASP3 P42574 2/20 0.37
MDM4 O15151 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28030548 0.93 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL27705197 0.91 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL7720044 0.90 KMT2A (0.58) KMT2AFABP5FABP7CA1CA2
SCHEMBL27564317 0.89 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL7036852 0.88 KMT2A (0.58) KMT2AFABP5FABP7CA1CA2
Cysteamine SCHEMBL28990896 0.87 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL30988970 0.87 KMT2A (0.54) KMT2AFABP5FABP7CA1CA2
SCHEMBL15058849 0.86 KMT2A (0.55) KMT2AFABP5FABP7CA1CA2
SCHEMBL12440444 0.85 KMT2A (0.58) KMT2AFABP5FABP7CA1CA2
SCHEMBL29171841 0.84 KMT2A (0.44) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735621-A1 NUCLEIC ACID SYNTHESIS ON REUSABLE SUPPORT DNA Script (FR) 2026-05-06 EP disclosed
US-20260028671-A1 Sequencing by Structure Assembly HARVARD COLLEGE (US) 2026-01-29 US disclosed
US-20250345792-A1 DEVICES AND METHODS FOR ANALYZING BIOLOGICAL SAMPLES CELLANOME. INC. 2025-11-13 US disclosed
US-12467086-B2 Sequencing by structure assembly PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-11-11 US disclosed
EP-4642926-A1 SPATIALLY BARCODED SURFACES Cellanome, Inc. (US) 2025-11-05 EP disclosed
US-20250320542-A1 SPATIALLY BARCODED SURFACES CELLANOME INC (US) 2025-10-16 US disclosed
US-12421628-B2 Massively parallel enzymatic synthesis of nucleic acid strands DNA SCRIPT (FR) 2025-09-23 US disclosed
US-20250243479-A1 BARCODED BEADS FOR SPATIAL ANALYSIS OF BIOMOLECULES MACEVICZ STEPHEN (US) 2025-07-31 US disclosed
US-20250215617-A1 MASSIVELY PARALLEL ENZYMATIC SYNTHESIS OF NUCLEIC ACID STRANDS DNA SCRIPT (FR) 2025-07-03 US disclosed
WO-2025072571-A1 CELL CULTURE WITHIN MICROFLUIDIC STRUCTURES Cellanome, Inc. (US) 2025-04-03 WO disclosed
US-20060194214-A1 Methods for assembly of high fidelity synthetic polynucleotides CODON DEVICES, INC. 2006-08-31 US disclosed
US-20060127920-A1 Polynucleotide synthesis PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-06-15 US disclosed
WO-2006044956-A1 METHODS FOR ASSEMBLY OF HIGH FIDELITY SYNTHETIC POLYNUCLEOTIDES CODON DEVICES, INC. (US) 2006-04-27 WO disclosed
WO-2005089110-A2 POLYNUCLEOTIDE SYNTHESIS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-09-29 WO disclosed
EP-1159285-B1 METHODS AND COMPOSITIONS FOR ECONOMICALLY SYNTHESIZING AND ASSEMBLING LONG DNA SEQUENCES METRIGEN INC (US) 2005-05-25 EP disclosed
US-20030232382-A1 Method and apparatus for performing large numbers of reactions using array assembly BRENNAN THOMAS M (US) 2003-12-18 US disclosed
US-6632641-B1 Filling wells in solid supports with reactants; releasing polynucleotides into solution in wells; amplification METRIGEN, INC. 2003-10-14 US disclosed
US-20030186226-A1 Methods and compositions for economically synthesizing and assembling long DNA sequences MOLINARI, ROBERT J., PH.D. AS COLLATERAL AGENT 2003-10-02 US disclosed
EP-1159285-A1 METHODS AND COMPOSITIONS FOR ECONOMICALLY SYNTHESIZING AND ASSEMBLING LONG DNA SEQUENCES Protogene Laboratories, Inc. (US) 2001-12-05 EP disclosed
WO-2000053617-A1 METHODS AND COMPOSITIONS FOR ECONOMICALLY SYNTHESIZING AND ASSEMBLING LONG DNA SEQUENCES PROTOGENE LABORATORIES, INC. (US) 2000-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028671-A1 Sequencing by Structure Assembly POLL, CPSF7, POLM KMT2A 3296/4885FABP5 2995/4885FABP7 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.