Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21948689 | 0.93 | IRAK4 (0.88) | IRAK4 | |
| SCHEMBL21949093 | 0.92 | IRAK4 (0.89) | IRAK4 | |
| SCHEMBL16873271 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16873267 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16873268 | 0.91 | IRAK4 (1.00) | IRAK4 | |
| Cyclopropane SCHEMBL16878892 | 0.89 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL24508743 | 0.88 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL29709746 | 0.88 | IRAK4 (0.84) | IRAK4 | |
| SCHEMBL21949048 | 0.86 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16873208 | 0.86 | IRAK4 (0.85) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089973-B1 | HETEROARYL SUBSTITUTED NICOTINAMIDE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-04-29 | — | — | EP | disclosed |