⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949106 | 0.89 | — | — | |
| SCHEMBL21949107 | 0.86 | — | — | |
| SCHEMBL23974178 | 0.64 | SLC6A2 (0.32) | — | |
| SCHEMBL21844961 | 0.59 | — | — | |
| SCHEMBL22150019 | 0.54 | SLC6A2 (0.31) | — | |
| SCHEMBL16878550 | 0.52 | — | — | |
| SCHEMBL22259089 | 0.52 | — | — | |
| SCHEMBL16877848 | 0.52 | — | — | |
| SCHEMBL16877712 | 0.51 | — | — | |
| SCHEMBL16877467 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |