SCHEMBL2194987

SCHEMBL2194987

C#C[Si](C)(C)CC[Si](C)(C)C#C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10731186 0.82
SCHEMBL19600557 0.79
SCHEMBL1126335 0.77
SCHEMBL5266758 0.75
SCHEMBL1275932 0.72
SCHEMBL698327 0.69
SCHEMBL4699 0.67
SCHEMBL2885270 0.67
SCHEMBL1332124 0.67
SCHEMBL2082322 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12279520-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-04-15 US disclosed
US-20240217992-A1 RETINOIC ACID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE Jiangxi Kerui Pharmaceutical Co., Ltd. (CN) 2024-07-04 US disclosed
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20210376261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-02 US disclosed
US-9518069-B2 Catalytic method for obtaining substituted (triorganosilyl)alkynes and their derivatives ADAM MICKIEWICZ UNIVERSITY (PL) 2016-12-13 US disclosed
EP-2658861-B1 NEW (TRIORGANOSILYL)ALKYNES AND THEIR DERIVATIVES AND A NEW CATALYTIC METHOD FOR OBTAINING NEW AND CONVENTIONAL SUBSTITUTED (TRIORGANOSILYL)ALKYNES AND THEIR DERIVATIVES UNIV ADAM MICKIEWICZ (PL) 2016-10-12 EP disclosed
US-20150361111-A1 Catalytic method for obtaining substituted (triorganosilyl)alkynes and their derivatives UNIV ADAM MICKIEWICZ (PL) 2015-12-17 US disclosed
US-9108994-B2 (Triorganosilyl)alkynes and their derivatives and a new catalytic method for obtaining new and conventional substituted (triorganosilyl)alkynes and their derivatives ADAM MICKIEWICZ UNIVERSITY (PL) 2015-08-18 US disclosed
US-8765719-B2 Therapeutic drug for adult T-cell leukemia KAGOSHIMA UNIVERSITY (JP) 2014-07-01 US disclosed
EP-2345409-A1 THERAPEUTIC AGENT FOR ADULT T-CELL LEUKEMIA Kagoshima University (JP) 2011-07-20 EP disclosed
US-20110172185-A1 THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA KAGOSHIMA UNIVERSITY (JP) 2011-07-14 US disclosed
US-20110172185-A1 THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA KAGOSHIMA UNIVERSITY (JP) 2011-07-14 US disclosed
US-20070111967-A1 Organosilicon compounds and their use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-17 US disclosed
EP-1572610-B1 METHOD FOR THE PRODUCTION OF 1.6-HEXANEDIOL BASF AG (DE) 2006-08-02 EP disclosed
EP-1562611-B1 HETEROCYCLIC SILICON COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH GNRH (GONADOTROPIN-RELEASING HORMONE) PARADIGM THERAPEUTICS LTD (GB) 2006-08-02 EP disclosed
US-20060052344-A1 Heterocyclic silicon compounds and their use in the treatment of diseases or conditions associated with gnrh (gonadotropin-releasing hormone) PARADIGM THERAPEUTICS LTD. (GB) 2006-03-09 US disclosed
EP-1562611-A1 HETEROCYCLIC SILICON COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH GNRH (GONADOTROPIN-RELEASING HORMONE) Amedis Pharmaceuticals Limited (GB) 2005-08-17 EP disclosed
WO-2004048390-A1 SILICON COMPOUNDS AMEDIS PHARMACEUTICALS LTD. (GB) 2004-06-10 WO disclosed
WO-2004045625-A1 HETEROCYCLIC SILICON COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH GNRH (GONADOTROPIN-RELEASING HORMONE) PARADIGM THERAPEUTICS LTD. (GB) 2004-06-03 WO disclosed