Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | NTSR2 | O95665 | 18/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 18/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195145 | 0.94 | XIAP (0.55) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL31084988 | 0.88 | NTSR2 (0.56) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL30311236 | 0.85 | XIAP (0.48) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL30874709 | 0.85 | XIAP (0.53) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL31385448 | 0.85 | NTSR2 (0.47) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL29470192 | 0.85 | ACE (0.50) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL30853507 | 0.84 | XIAP (0.48) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL31289489 | 0.84 | XIAP (0.52) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL29572637 | 0.84 | DPP4 (0.47) | XIAPNTSR2NTSR1SORT1 | |
| Acetic Acid SCHEMBL30311279 | 0.84 | ELANE (0.47) | XIAPNTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2019-03-07 | — | — | US | disclosed |
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | XIAP 264/4885NTSR2 441/4885NTSR1 259/4885 |
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | XIAP 264/4885NTSR2 441/4885NTSR1 259/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | XIAP 443/4885NTSR2 582/4885NTSR1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.