Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.74 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.55 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846993 | 0.85 | EGFR (1.00) | EGFRMETALKKCNH2INSR | |
| SCHEMBL21847020 | 0.84 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL26611718 | 0.81 | EGFR (0.73) | EGFRMETALKIGF1RKCNH2 | |
| SCHEMBL21846975 | 0.76 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL26970210 | 0.76 | EGFR (0.63) | EGFRMETALKIGF1RCAMK2D | |
| SCHEMBL30689961 | 0.76 | EGFR (0.63) | EGFRMETALKIGF1RCAMK2D | |
| SCHEMBL21847011 | 0.75 | EGFR (1.00) | EGFRMETALKKCNH2INSR | |
| SCHEMBL21846976 | 0.75 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL21846990 | 0.74 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL29526468 | 0.74 | EGFR (0.67) | EGFRMETALKCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-A1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | Korea Research Institute of Chemical Technology (KR) | 2020-04-22 | — | — | EP | disclosed |