Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.94 |
| ▸ | MET | P08581 | 1/20 | 0.76 |
| ▸ | INSR | P06213 | 1/20 | 0.70 |
| ▸ | IGF1R | P08069 | 1/20 | 0.70 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.70 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847009 | 0.97 | EGFR (1.00) | EGFRMETINSRIGF1RALK | |
| SCHEMBL21846980 | 0.92 | EGFR (1.00) | EGFRMETINSRIGF1RALK | |
| SCHEMBL21847006 | 0.88 | EGFR (1.00) | EGFRMETALKLRRK2 | |
| SCHEMBL21846983 | 0.88 | EGFR (1.00) | EGFRMETLRRK2 | |
| SCHEMBL21846990 | 0.86 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL21846971 | 0.86 | EGFR (1.00) | EGFRMET | |
| SCHEMBL21847014 | 0.84 | EGFR (1.00) | EGFRMETALK | |
| SCHEMBL29609251 | 0.84 | EGFR (1.00) | EGFRINSRIGF1RALKLRRK2 | |
| SCHEMBL21847015 | 0.84 | EGFR (1.00) | EGFRINSRIGF1RALKLRRK2 | |
| SCHEMBL21846970 | 0.84 | EGFR (1.00) | EGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640246-A1 | N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | Korea Research Institute of Chemical Technology (KR) | 2020-04-22 | — | — | EP | disclosed |