SCHEMBL21954697

SCHEMBL21954697

CC(C)C(=O)C12CCC(C(=O)O)(CC1)C2

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 2/20 0.34
FFAR3 O14843 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913365 0.86 GRM1 (0.41) GRM1FFAR3
SCHEMBL19757727 0.86 FFAR3 (0.36) GRM1FFAR3
SCHEMBL478303 0.80 GRM1 (0.40) GRM1FFAR3
SCHEMBL21954700 0.76
SCHEMBL16933182 0.74 GRM1 (0.40) GRM1FFAR3
SCHEMBL16892283 0.73 FFAR3 (0.38) GRM1FFAR3
SCHEMBL23904374 0.73 GRM1 (0.43) GRM1FFAR3
SCHEMBL10151921 0.72 GRM1 (0.36) GRM1FFAR3
SCHEMBL16185854 0.71
SCHEMBL15114105 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919937-B2 Bicyclic peptide ligands and uses thereof BICYCLETX LIMITED (GB) 2021-02-16 US disclosed
US-20200131228-A1 BICYCLIC PEPTIDE LIGANDS AND USES THEREOF BICYCLETX LIMITED (GB) 2020-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131228-A1 BICYCLIC PEPTIDE LIGANDS AND USES THEREOF VIP, NGLY1, BID GRM1 1648/4885FFAR3 560/4885
US-10919937-B2 Bicyclic peptide ligands and uses thereof VIP, NGLY1, BID GRM1 1648/4885FFAR3 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.