Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940449 | 1.00 | MAOB (0.45) | MAOBHRH3PARP10CYP2D6PARP15 | |
| SCHEMBL1940994 | 0.84 | MAOB (0.50) | MAOBHRH3PARP10PARP15MAOA | |
| SCHEMBL1941861 | 0.84 | MAOB (0.50) | MAOBHRH3PARP10PARP15MAOA | |
| SCHEMBL1940216 | 0.83 | MAOB (0.51) | MAOBHRH3PARP10PARP15MAOA | |
| SCHEMBL10252515 | 0.77 | PARP10 (0.53) | MAOBPARP10PARP15MAOANOX1 | |
| SCHEMBL2997270 | 0.75 | MAOB (0.62) | MAOBPARP10PARP15MAOANOX1 | |
| SCHEMBL19189961 | 0.74 | GAA (0.41) | — | |
| Hydrochloric Acid SCHEMBL9015457 | 0.74 | MAOB (0.61) | MAOBPARP10PARP15MAOANOX1 | |
| SCHEMBL27683488 | 0.74 | MAOB (0.61) | MAOBPARP10PARP15MAOANOX1 | |
| SCHEMBL2196861 | 0.74 | EPHX2 (0.47) | MAOBPARP10PARP15MAOANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237624-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | LABORATOIRE THERAMEX (MC) | 2011-09-29 | — | — | US | disclosed |
| US-7977364-B2 | Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents | LABORATOIRE THERMAMEX (MC) | 2011-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237624-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | ESR1, ESR2, GPER1 | MAOB 1421/4885HRH3 577/4885PARP10 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.