⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468107 | 0.97 | MEN1 (0.30) | — | |
| SCHEMBL51000 | 0.93 | — | — | |
| SCHEMBL220749 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL3683039 | 0.89 | TSHR (0.30) | — | |
| SCHEMBL3682811 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL3673825 | 0.89 | TSHR (0.30) | — | |
| SCHEMBL7620160 | 0.87 | — | — | |
| SCHEMBL9148014 | 0.87 | MEN1 (0.33) | — | |
| SCHEMBL9124662 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL15435869 | 0.86 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395459-A1 | THERMOSETTING RESIN COMPOSITION AND METHOD FOR MANUFACTURING SAME | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-12-23 | — | — | US | disclosed |
| US-9072791-B2 | Photostabilized pharmaceutical compositions | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2015-07-07 | — | — | US | disclosed |
| US-8088916-B2 | Hyaluronic acid-methotrexate conjugate | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20110245276-A1 | PHOTOSTABILIZED PHARMACEUTICAL COMPOSITIONS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2343078-A1 | LIGHT-STABILIZED PHARMACEUTICAL COMPOSITION | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-7807675-B2 | methotrexate- alpha -PhePhe-NHC10H20O3NHCO O-hyaluronic acid; therapeutical agent; oseoarthritis (degenerative diseases ) | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20090093414-A1 | Hyaluronic Acid-Methotrexate Conjugate | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20080014288-A1 | Zinc-containing treatments for hyperphosphatemia | GENZYME CORPORATION | 2008-01-17 | — | — | US | disclosed |
| EP-1830832-A1 | ZINC-CONTAINING TREATMENTS FOR HYPERPHOSPHATEMIA | Genzyme Corporation (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20070197465-A1 | Hyaluronic Acid-Methotrexate Conjugate | DENKI KAGAKU KABUSHIKI KAISHA (JP) | 2007-08-23 | — | — | US | disclosed |
| US-5461051-A | Tetracyclic compounds having anti-allergic and anti-asthmatic activities and their use | SANKYO COMPANY, LIMITED (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0648827-A1 | Reactive liquid crystal compounds | MERCK PATENT GmbH (DE) | 1995-04-19 | — | — | EP | disclosed |
| US-5362725-A | Antiallergens, antiasthmatic | SANKYO COMPANY, LIMITED (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0615630-A1 | LIQUID CRYSTALLINE MATERIAL | MERCK PATENT GmbH (DE) | 1994-09-21 | — | — | EP | disclosed |
| WO-1994008268-A1 | LIQUID CRYSTALLINE MATERIAL | MERCK PATENT GMBH (DE) | 1994-04-14 | — | — | WO | disclosed |
| EP-0591508-A1 | ELECTROOPTICAL LIQUID CRYSTAL SYSTEM | MERCK PATENT GmbH (DE) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993022397-A1 | ELECTROOPTICAL LIQUID CRYSTAL SYSTEM | MERCK PATENT GMBH (DE) | 1993-11-11 | — | — | WO | disclosed |
| EP-0505014-A2 | Novel tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use | Sankyo Company Limited (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0421823-A2 | Novel tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use | Sankyo Company Limited (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4059581-A | Heterocyclic nitrogen containing siloxanes | UNION CARBIDE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |