(E)-4-Styrylaniline

(E)-4-Styrylaniline

SCHEMBL219628

Nc1ccc(C=Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 1.00
MAOB P27338 3/20 1.00
MAOA P21397 2/20 1.00
APP P05067 2/20 0.61
NFE2L2 Q16236 1/20 0.56
CYP1B1 Q16678 1/20 0.55
TSHR P16473 1/20 0.53
RELA Q04206 2/20 0.50
TRPA1 O75762 1/20 0.50
CYP3A4 P08684 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GRM4 Q14833 1/20 0.48
NQO2 P16083 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(E)-4-Styrylaniline SCHEMBL219627 1.00 CYP19A1 (1.00) CYP19A1MAOBMAOAAPPNFE2L2
(E)-4-Styrylaniline SCHEMBL6757469 1.00 CYP19A1 (1.00) CYP19A1MAOBMAOAAPPNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL3080968 0.97 CYP19A1 (0.95) CYP19A1MAOBMAOAAPPNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL3080965 0.97 CYP19A1 (0.95) CYP19A1MAOBMAOAAPPNFE2L2
SCHEMBL14160333 0.93 CYP19A1 (0.86) CYP19A1MAOBMAOAAPPNFE2L2
(Z)-1,2-Diphenylethene SCHEMBL28271500 0.92 CYP19A1 (0.84) CYP19A1MAOBMAOAAPPNFE2L2
Biphenyl SCHEMBL6836020 0.90 CYP19A1 (0.81) CYP19A1MAOBMAOAAPPNFE2L2
Biphenyl SCHEMBL6836018 0.90 CYP19A1 (0.81) CYP19A1MAOBMAOAAPPNFE2L2
SCHEMBL13925229 0.90 CYP19A1 (0.81) CYP19A1MAOBMAOAAPPNFE2L2
SCHEMBL19772768 0.90 CYP19A1 (0.81) CYP19A1MAOBMAOAAPPNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350563-B Polymer capable of being assembled with protein and hydrophobic small molecule medicine and preparation method thereof 至微(深圳)医学科技有限公司 2025-04-04 CN claimed
CN-119350563-A Polymer capable of being assembled with protein and hydrophobic small molecule medicine and preparation method thereof 至微(深圳)医学科技有限公司 2025-01-24 CN claimed
CN-116943631-B Nanometer titanium dioxide-zinc oxide composite material 凯里学院 2024-11-15 CN claimed
CN-115785513-B Weak acid substrate with high specific surface area and application thereof 佛山市云米电器科技有限公司 2023-11-03 CN claimed
CN-116943631-A Nanometer titanium dioxide-zinc oxide composite material 凯里学院 2023-10-27 CN claimed
CN-115785513-A Weak acid base material with high specific surface area and application thereof 佛山市云米电器科技有限公司 2023-03-14 CN claimed
CN-109054743-A A kind of medical instrument absorbing material and preparation method thereof 湖南博隽生物医药有限公司 2018-12-21 CN claimed
CN-108084435-A A kind of high-modulus high temperature resistant bimaleimide resin composition 江苏恒神股份有限公司 2018-05-29 CN claimed
CN-101560223-B Phosphoryl amino acid stilbene derivative, preparing method and application thereof GRADUATE SCHOOL AT SHENZHEN, TSINGHUA UNIVERSITY (CN) 2011-12-07 CN claimed
CN-101602820-B Synthesis and application of p-methoxyl-containing Schiff base type visible light photosensitizer with conjugated structure UNIV CHONGQING 2011-03-30 CN claimed
CN-101602819-A Contain the synthetic and application of the visible light photosensitizer with conjugated structure schiff base type of adjacent hydroxyl UNIV CHONGQING (CN) 2009-12-16 CN claimed
CN-101602821-A Contain synthetic and application to the visible light photosensitizer with conjugated structure schiff base type of hydroxyl UNIV CHONGQING (CN) 2009-12-16 CN claimed
CN-101602820-A Contain synthetic and application to the visible light photosensitizer with conjugated structure schiff base type of methoxyl group UNIV CHONGQING (CN) 2009-12-16 CN claimed
CN-101560223-A Phosphoryl amino acid stilbene derivative, preparing method and application thereof UNIV TSINGHUA GRADUATE SCHOOL (CN) 2009-10-21 CN claimed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5122563-A Heat resistant; composites, adhesives; amine having at least one trifluoromethyl group AMERICAN CYANAMID COMPANY (US) 1992-06-16 US claimed
US-5061781-A From dianhydrides and either diaminobenzotrifluoromethanes or bis(trifluoromethyl) oxydianilines and endcapped AMERICAN CYANAMID COMPANY (US) 1991-10-29 US claimed