Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 7/20 | 0.48 |
| ▸ | PFKFB2 | O60825 | 6/20 | 0.48 |
| ▸ | PFKFB1 | P16118 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1294945 | 0.81 | HDAC2 (0.60) | CTSCHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1294947 | 0.81 | HDAC2 (0.60) | CTSCHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7692266 | 0.80 | HDAC2 (0.50) | CTSCGAAHDAC3HDAC4HDAC1 | |
| SCHEMBL7692271 | 0.80 | HDAC2 (0.50) | CTSCGAAHDAC3HDAC4HDAC1 | |
| SCHEMBL10327019 | 0.79 | SCN4A (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12837649 | 0.79 | HDAC1 (0.49) | CTSCHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2200641 | 0.79 | CYP2C19 (0.56) | KMT2ACTSCHDAC3HDAC4HDAC1 | |
| SCHEMBL12649141 | 0.79 | HDAC2 (0.52) | KMT2ACTSCHDAC3HDAC4HDAC1 | |
| SCHEMBL2200636 | 0.79 | CYP2C19 (0.56) | KMT2ACTSCHDAC3HDAC4HDAC1 | |
| SCHEMBL10326402 | 0.79 | SCN4A (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643703-A1 | EP300/CREBBP INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |