Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492830 | 0.85 | KMT2A (0.70) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL11987662 | 0.84 | NPSR1 (0.76) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL2198809 | 0.84 | KMT2A (0.68) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL12649100 | 0.84 | KMT2A (0.68) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL11987493 | 0.84 | KMT2A (0.68) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL8871429 | 0.84 | KMT2A (0.68) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL12105308 | 0.82 | KMT2A (0.66) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL8251291 | 0.82 | MEN1 (0.66) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL15457836 | 0.82 | KMT2A (0.66) | KMT2AMEN1LMNANPSR1NPC1 | |
| SCHEMBL11987478 | 0.82 | KMT2A (0.66) | KMT2AMEN1LMNANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643703-A1 | EP300/CREBBP INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |