Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195678 | 0.91 | GCK (0.48) | GCKNAMPTPDE4A | |
| SCHEMBL2196483 | 0.88 | GCK (0.46) | GCKNAMPT | |
| SCHEMBL2203083 | 0.86 | GCK (0.46) | GCKNAMPT | |
| SCHEMBL2347451 | 0.82 | GCK (0.71) | GCK | |
| SCHEMBL2196267 | 0.82 | GCK (0.70) | GCK | |
| SCHEMBL2195649 | 0.81 | GCK (0.45) | GCK | |
| SCHEMBL2197921 | 0.80 | GCK (0.71) | GCK | |
| SCHEMBL2195760 | 0.80 | GCK (0.70) | GCK | |
| SCHEMBL2198311 | 0.74 | GCK (0.60) | GCK | |
| SCHEMBL2196374 | 0.73 | GCK (0.51) | GCKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |