Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | SCN2B | O60939 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.47 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880152 | 0.89 | SCN9A (0.61) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| Pf-05089771 SCHEMBL30543444 | 0.79 | SCN9A (0.65) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| Pf-05089771 SCHEMBL21968007 | 0.79 | SCN9A (0.65) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| Pf-05089771 SCHEMBL25819004 | 0.76 | SCN9A (0.77) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| SCHEMBL14889772 | 0.75 | SCN9A (0.54) | SCN9ACYP2C9SCN5ASCN1ASCN2A | |
| SCHEMBL14889827 | 0.74 | SCN9A (0.55) | SCN9ACYP2C9SCN5ASCN1ASCN2A | |
| SCHEMBL16531476 | 0.70 | SCN9A (0.75) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| SCHEMBL14889562 | 0.70 | SCN9A (0.55) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| SCHEMBL16531192 | 0.70 | SCN9A (0.77) | SCN9ACYP2C9SCN5ASCN2BSCN1A | |
| SCHEMBL18013128 | 0.69 | SCN9A (0.64) | SCN9ACYP2C9SCN5ASCN2BSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155837-A1 | PHARMACEUTICAL COMPOSITION HAVING ANALGESIC AND/OR ANTIPRURITIC FUNCTION AND USE THEREOF | 昆山彭济凯丰生物科技有限公司 | 2023-08-24 | — | — | WO | disclosed |
| US-10662229-B2 | Spider venom peptides and methods of use for modulating sodium channels | THE UNIVERSITY OF QUEENSLAND (AU) | 2020-05-26 | — | — | US | disclosed |