SCHEMBL21968720

SCHEMBL21968720

c1ccc(N(c2ccccc2)c2ccc3oc4cc(N(c5ccc6ccccc6c5)c5ccc6c(c5)oc5ccccc56)ccc4c3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
HPGD P15428 5/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 4/20 0.41
NPC1 O15118 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 3/20 0.41
AHR P35869 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GLA P06280 2/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.36
GPR55 Q9Y2T6 1/20 0.35
CYP1A2 P05177 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24154579 0.97 MAPT (0.42) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL21966504 0.97 KDM4E (0.37) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL24153682 0.97 MAPT (0.42) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL24153679 0.96 MAPT (0.41) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL19998805 0.96 AHR (0.44) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL19998667 0.96 KDM4E (0.44) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL22506056 0.93 MAPT (0.38) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL24153676 0.93 AHR (0.46) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL24153778 0.93 MAPT (0.46) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL21968660 0.92 HCRTR1 (0.38) MAPTHPGDKDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200176685-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-06-04 US disclosed
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed
US-20200144510-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 MAPT 2375/4885HPGD 2197/4885KDM4E 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.