Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 14/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177869 | 0.79 | GCK (0.44) | PIK3C3GCKLNPEP | |
| SCHEMBL2198311 | 0.78 | GCK (0.60) | PIK3C3GCKLNPEP | |
| SCHEMBL2180026 | 0.71 | GCK (0.48) | GCK | |
| SCHEMBL2196374 | 0.70 | GCK (0.51) | GCKNAMPT | |
| SCHEMBL2177573 | 0.68 | GCK (0.43) | GCKNAMPT | |
| SCHEMBL2280345 | 0.68 | GCK (0.47) | GCKNAMPT | |
| SCHEMBL2280341 | 0.68 | GCK (0.47) | GCKNAMPT | |
| SCHEMBL2180158 | 0.67 | GCK (0.46) | GCK | |
| SCHEMBL2198514 | 0.67 | GCK (0.50) | GCKNAMPT | |
| SCHEMBL2415677 | 0.67 | CDK1 (0.34) | GCKLNPEPCDK1CDK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |