SCHEMBL21969116

SCHEMBL21969116

CCCCc1ccc(Nc2ccc(Nc3ccc(CCCC)cc3)c3c2C(=O)c2c(Sc4ccccc4)ccc(Sc4ccccc4)c2C3=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.42
▸ MAPK1 P28482 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ TRPV1 Q8NER1 1/20 0.39
▸ METAP2 P50579 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ NSD2 O96028 1/20 0.38
▸ HPGD P15428 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ TP53 P04637 1/20 0.37
▸ XBP1 P17861 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14507795 0.94 HPGD (0.40) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL13110649 0.87 HPGD (0.36) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL1476038 0.83 HPGD (0.50) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL10935194 0.82 MAPT (0.50) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL11603194 0.82 MAPT (0.50) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL14508831 0.82 MAPT (0.50) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL14508830 0.80 P2RY2 (0.36) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL10732288 0.80 NPC1 (0.62) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL29699621 0.79 UNG (0.51) MAPTMAPK1LMNAMEN1NPC1
SCHEMBL14508827 0.78 P2RY2 (0.36) MAPTLMNAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11173694-B2 Laminate, manufacturing method of laminate, and image display device FUJIFILM CORPORATION (JP) 2021-11-16 — — US disclosed
US-11148404-B2 — — 2021-10-19 — — US disclosed
US-20200139691-A1 LAMINATE, MANUFACTURING METHOD OF LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2020-05-07 — — US disclosed
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