Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529595 | 1.00 | KMT2A (0.50) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL1413268 | 1.00 | KMT2A (0.50) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL5784676 | 1.00 | KMT2A (0.50) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL31181835 | 1.00 | KMT2A (0.50) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL2195961 | 1.00 | KMT2A (0.50) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL1879002 | 0.89 | KMT2A (0.61) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL1879606 | 0.89 | KMT2A (0.61) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL29741068 | 0.89 | KMT2A (0.61) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL1872298 | 0.89 | KMT2A (0.61) | KMT2ADRD2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL23782820 | 0.79 | EPAS1 (0.45) | KMT2ACYP11B1CYP11B2S1PR1EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256288-A | A method of preparing (S) -1- amino -2,3- dihydro -1H- indenes -4- formonitrile HCN | 苏州山青竹生物医药有限公司 | 2019-09-20 | — | — | CN | claimed |
| US-20260125359-A1 | HETEROARYL COMPOUNDS AS MULTI-TARGET PROTEIN KINASE INHIBITORS | FUJIAN HAIXI PHARMACEUTICALS CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
| EP-3518922-B1 | COMPOUNDS AND METHODS FOR TREATING LUPUS | RECEPTOS LLC (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-3856738-B1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | QUIM SINTETICA S A (ES) | 2025-03-19 | — | — | EP | disclosed |
| EP-2498610-B2 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | Química Sintética, S.A. (ES) | 2022-10-11 | — | — | US | disclosed |
| US-11278526-B2 | Compounds and methods for treating lupus | RECEPTOS LLC (US) | 2022-03-22 | — | — | US | disclosed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | disclosed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | disclosed |
| CN-113698319-A | Preparation method of ozapimod intermediate | 偶极医药科技(徐州)有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-102762100-B | Selective sphingosine-1-phosphate receptor modulators and chiral synthesis methods | RECEPTOS INC | 2015-07-01 | — | — | CN | disclosed |
| WO-2015066515-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND COMBINATION THERAPY THEREWITH | RECEPTOS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |
| US-20130231326-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130231326-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-8362048-B2 | Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362048-B2 | Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| CN-102762100-A | Selective sphingosine-1-phosphate receptor modulators and chiral synthesis methods | RECEPTOS INC | 2012-10-31 | — | — | CN | disclosed |
| US-20110172202-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC | 2011-07-14 | — | — | US | disclosed |
| US-20110172202-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS LLC | 2011-07-14 | — | — | US | disclosed |
| WO-2011060392-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278526-B2 | Compounds and methods for treating lupus | S1PR1, S1PR2, SSB | KMT2A 1801/4885DRD2 3747/4885CYP11B1 1537/4885 |
| US-20110172202-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | S1PR1, S1PR3, S1PR2 | KMT2A 4226/4885DRD2 2358/4885CYP11B1 519/4885 |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | S1PR1, S1PR4, S1PR3 | KMT2A 3393/4885DRD2 1733/4885CYP11B1 1525/4885 |
| US-20260125359-A1 | HETEROARYL COMPOUNDS AS MULTI-TARGET PROTEIN KINASE INHIBITORS | ERBB2, ERBB3, ARRB1 | KMT2A 2787/4885DRD2 3071/4885CYP11B1 644/4885 |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | S1PR1, S1PR4, S1PR3 | KMT2A 3393/4885DRD2 1733/4885CYP11B1 1525/4885 |
| US-20130231326-A1 | SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | S1PR1, S1PR3, S1PR2 | KMT2A 4230/4885DRD2 2353/4885CYP11B1 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.