Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081620 | 0.87 | ATM (0.54) | CARM1PRMT6PRMT8ATMTAAR1 | |
| SCHEMBL2346063 | 0.85 | CARM1 (0.63) | CARM1PRMT6PRMT8TAAR1AOC3 | |
| SCHEMBL11402252 | 0.84 | HRH3 (0.53) | ATMTAAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL18687449 | 0.83 | TAAR1 (0.49) | CARM1PRMT6PRMT8TAAR1MEN1 | |
| Hydrochloric Acid SCHEMBL3665790 | 0.83 | CARM1 (0.61) | CARM1PRMT6PRMT8TAAR1AOC3 | |
| SCHEMBL29860798 | 0.83 | CARM1 (0.61) | CARM1PRMT6PRMT8TAAR1AOC3 | |
| SCHEMBL28789449 | 0.83 | CARM1 (0.49) | CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL20067552 | 0.83 | HTT (0.50) | ATMTAAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL15466880 | 0.82 | MAOB (0.50) | ATMTAAR1TSHRKDM4ECNR2 | |
| SCHEMBL4922897 | 0.81 | MEN1 (0.52) | CARM1PRMT6PRMT8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153510-B1 | FUSED AZINES AS CHEMOKINE CXCR4 RECEPTOR MODULATORS AND USES RELATED THERETO | UNIV EMORY (US) | 2020-05-06 | — | — | EP | disclosed |