⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21970062 | 0.82 | — | — | |
| SCHEMBL21969686 | 0.78 | — | — | |
| SCHEMBL21970057 | 0.78 | — | — | |
| SCHEMBL17754740 | 0.73 | — | — | |
| SCHEMBL25843988 | 0.71 | — | — | |
| SCHEMBL20332448 | 0.69 | — | — | |
| SCHEMBL19405008 | 0.67 | — | — | |
| SCHEMBL21130353 | 0.67 | — | — | |
| SCHEMBL18743154 | 0.67 | — | — | |
| SCHEMBL21366520 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140438-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF GROUP II METABOTROPIC GLUTAMATE RECEPTORS | DOMAIN THERAPEUTICS (FR) | 2020-05-07 | — | — | US | disclosed |