SCHEMBL21972080

SCHEMBL21972080

Cc1c(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)ccc2sc3cccc(-c4cc(C(C)(C)C)cc(C(C)(C)C)c4)c3c12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRB P28702 8/20 0.34
▸ RXRA P19793 7/20 0.34
▸ RXRG P48443 3/20 0.34
▸ RARA P10276 1/20 0.34
▸ TNF P01375 1/20 0.33
▸ NOD1 Q9Y239 1/20 0.33
▸ BTK Q06187 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ PLA2G1B P04054 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ CASP3 P42574 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31
▸ SENP8 Q96LD8 1/20 0.31
▸ SENP7 Q9BQF6 1/20 0.31
▸ SENP6 Q9GZR1 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22199310 0.95 RXRB (0.36) RXRBRXRARXRGRARATNF
SCHEMBL24433571 0.86 RXRB (0.33) RXRBRXRARXRGRARATNF
SCHEMBL21972075 0.85 RXRB (0.37) RXRBRXRARXRGRARATNF
SCHEMBL22199334 0.84 KDM4E (0.33) RXRBRXRARXRGTNFNOD1
SCHEMBL26194981 0.83 TSHR (0.31) RXRBRXRAALDH1A1
SCHEMBL24311312 0.82 RXRB (0.36) RXRBRXRARXRGRARATNF
SCHEMBL26199131 0.82 TNF (0.33) RXRBRXRARXRGTNFNOD1
SCHEMBL24433670 0.81 RXRB (0.36) RXRBRXRARXRGRARATNF
SCHEMBL25768528 0.81 RXRB (0.36) RXRBRXRARXRGRARATNF
SCHEMBL25768516 0.81 CNR1 (0.36) RXRBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 — — US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 RXRB 1833/4885RXRA 1861/4885RXRG 1895/4885
US-11802136-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 RXRB 1833/4885RXRA 1861/4885RXRG 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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