SCHEMBL219727

SCHEMBL219727

CC(C)N1CCC(N(Cc2ccc3onc(N)c3c2)S(=O)(=O)CCNC(=O)c2ccc(Cl)s2)CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220224 0.82 F10 (0.57) F10
SCHEMBL222060 0.81 F10 (0.55) F10
SCHEMBL3882262 0.81 F10 (0.33) F10
SCHEMBL3882259 0.80 F10 (0.35) F10
SCHEMBL221782 0.80 F10 (0.57) F10
SCHEMBL219979 0.79 F10 (0.58) F10
SCHEMBL219860 0.78 F10 (0.65) F10
SCHEMBL221194 0.77 F10 (0.59) F10
SCHEMBL221417 0.77 F10 (0.63) F10
SCHEMBL219872 0.77 F10 (0.63) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088925-B2 low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents SANOFI-AVENTIS (FR) 2012-01-03 US disclosed