⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688061 | 1.00 | — | — | |
| SCHEMBL963751 | 0.93 | — | — | |
| SCHEMBL10743755 | 0.91 | HPGD (0.36) | — | |
| SCHEMBL11565964 | 0.87 | — | — | |
| SCHEMBL2198239 | 0.86 | — | — | |
| SCHEMBL2199616 | 0.84 | EPHX1 (0.47) | — | |
| SCHEMBL2002222 | 0.84 | EPHX1 (0.42) | — | |
| SCHEMBL2197798 | 0.79 | EPHX1 (0.42) | — | |
| SCHEMBL6450396 | 0.79 | EPHX1 (0.50) | — | |
| SCHEMBL8280 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101311176-A | Isoquinoline compounds, preparation method and use thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-11-26 | — | — | CN | claimed |
| US-12600726-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2026-04-14 | — | — | US | disclosed |
| EP-3651762-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-3651762-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-117736196-A | Pyridine amide derivative and application thereof | 顺毅股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116348455-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230019236-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
| US-20220048913-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2022-02-17 | — | — | US | disclosed |
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1898239-A | Novel diazaspiroalkanes and their use in the treatment of CCR8 mediated diseases | ASTRAZENECA AB (SE) | 2007-01-17 | — | — | CN | disclosed |
| CN-1711243-A | 2-pyridone derivatives as inhibitors of neutrophil elastase | ASTRAZENECA AB (SE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1708499-A | Purine compounds and their use as cannabinoid receptor ligands | PFIZER (US) | 2005-12-14 | — | — | CN | disclosed |
| CN-1649859-A | Substituted phenylacetamides and their use as glucokinase activators | HOFFMANN LA ROCHE (CH) | 2005-08-03 | — | — | CN | disclosed |
| CN-1505613-A | Substituted indoles, pharmaceutical compositions containing such indoles and their use as ppar-gamma binding agents | ʷ��˿�������ȳ�ķ����˾ | 2004-06-16 | — | — | CN | disclosed |
| CN-1105706-C | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 2003-04-16 | — | — | CN | disclosed |
| CN-1305993-A | Cyclic guanyl preparation used as nitrogen oxide synthetic enzyme inhibitor | SEARLE & CO (US) | 2001-08-01 | — | — | CN | disclosed |
| CN-1189823-A | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 1998-08-05 | — | — | CN | disclosed |
| CN-86108233-A | The composition of heterogeneous ring compound nematocides and sterilant | — | 1987-09-23 | — | — | CN | disclosed |