Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.78 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.78 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.78 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.78 |
| ▸ | HTR3B | O95264 | 1/20 | 0.78 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.78 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.78 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.78 |
| ▸ | HTR2B | P41595 | 1/20 | 0.78 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.78 |
| ▸ | HTR3A | P46098 | 1/20 | 0.78 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.78 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.78 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.78 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834638 | 0.91 | CYP3A4 (0.76) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| Hydrochloric Acid SCHEMBL7407971 | 0.90 | CYP3A4 (0.75) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| SCHEMBL9835755 | 0.89 | CYP3A4 (0.74) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| SCHEMBL9837125 | 0.89 | CYP3A4 (0.74) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| SCHEMBL9837022 | 0.88 | CYP3A4 (0.72) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| SCHEMBL7408093 | 0.88 | CYP3A4 (0.72) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| SCHEMBL443444 | 0.88 | CYP3A4 (0.72) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| (R)-Ondansetron SCHEMBL848379 | 0.88 | CYP3A4 (1.00) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| (S)-Ondansetron SCHEMBL4543 | 0.88 | CYP3A4 (1.00) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E | |
| Ondansetron SCHEMBL1560211 | 0.88 | CYP3A4 (1.00) | CYP3A4KCNH2CYP1A2CYP2D6HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200138964-A1 | TERTIARY AMINE COMPOUND OR IMINE COMPOUND-POLYMER CONJUGATE AND PRODUCTION METHOD THEREFOR | SEIKAGAKU CORPORATION (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138964-A1 | TERTIARY AMINE COMPOUND OR IMINE COMPOUND-POLYMER CONJUGATE AND PRODUCTION METHOD THEREFOR | SOAT1, SLC7A1, ODC1 | CYP3A4 1037/4885KCNH2 1160/4885CYP1A2 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.