Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976290 | 0.87 | HDAC6 (0.72) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229603 | 0.85 | HDAC6 (0.86) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18237041 | 0.84 | HDAC6 (0.76) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229678 | 0.83 | HDAC6 (0.81) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229475 | 0.82 | HDAC6 (0.86) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL20088848 | 0.82 | HDAC6 (0.78) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229615 | 0.82 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18237054 | 0.82 | HDAC6 (0.95) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229659 | 0.82 | HDAC6 (0.72) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18229717 | 0.81 | HDAC6 (0.78) | HDAC6HDAC3HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294715-B1 | BENZIMIDAZOLE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY | KANCERA AB (SE) | 2020-05-06 | — | — | EP | disclosed |