SCHEMBL21977481

SCHEMBL21977481

C[Si]1(CCl)OCCOCCO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21977534 0.77
SCHEMBL21977491 0.75
SCHEMBL21977498 0.74 TTR (0.32) TTR
SCHEMBL21977521 0.74 TTR (0.32) TTR
SCHEMBL21977477 0.70
SCHEMBL21977520 0.69
SCHEMBL1629107 0.67 TTR (0.43) TTR
SCHEMBL9861537 0.67 TTR (0.43) TTR
SCHEMBL1628524 0.67 TTR (0.43) TTR
SCHEMBL1629140 0.67 TTR (0.43) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312734-B2 Nitrogen-containing cyclic organoxysilane compound and method for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-26 US disclosed
EP-3660025-B1 NITROGEN-CONTAINING CYCLIC ORGANOXYSILANE COMPOUND AND METHOD FOR PRODUCING THE SAME SHINETSU CHEMICAL CO (JP) 2022-03-23 EP disclosed
EP-3660025-A1 NITROGEN-CONTAINING CYCLIC ORGANOXYSILANE COMPOUND AND METHOD FOR PRODUCING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2020-06-03 EP disclosed
CN-111217849-A Nitrogen-containing cyclic organooxysilane compound and method for producing same 信越化学工业株式会社 2020-06-02 CN disclosed
US-20200165276-A1 NITROGEN-CONTAINING CYCLIC ORGANOXYSILANE COMPOUND AND METHOD FOR PRODUCING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312734-B2 Nitrogen-containing cyclic organoxysilane compound and method for producing the same OR10J3, HRH3, HRH4 TTR 1578/4885
US-20200165276-A1 NITROGEN-CONTAINING CYCLIC ORGANOXYSILANE COMPOUND AND METHOD FOR PRODUCING THE SAME OR10J3, HRH3, HRH4 TTR 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.